[vc_row full_width=”stretch_row” content_placement=”middle” el_class=”ServicetopHero” css=”.vc_custom_1514972294246{background-image: url(https://ivflondon.teampumpkin.com/wp-content/uploads/2018/01/pgsherobanner.jpg?id=2307) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_custom_heading text=”PGT-A (Preimplantation Genetic
Testing for Aneuploidy)” font_container=”tag:h1|text_align:right|color:%2346b4cd”][vc_column_text el_class=”ServicesHeroSubtitleBlue”]
The selection of ‘normal or Euploid’ embryo(s)
following genetic testing before a transfer procedure
[/vc_column_text][/vc_column][/vc_row][vc_row full_width=”stretch_row” el_class=”IntroBoxesRow”][vc_column el_class=”ServiceIntroboxLeftWhite”][TS-VCSC-Icon-Box-Tiny style=”boxed_left” box_background_color=”” padding_custom=”true” padding_outside=”40″ title=”Introduction to Preimplantation Genetic Screening” title_wrap=”h2″ font_title_family=”Default:regular” title_size=”14″ title_color=”#46b4cd” title_align=”left” title_spacing=”0″ font_content_family=”Default:regular” line_height=”18″ icon_size_slide=”16″ icon_padding=”0″ el_class=”bluecres” conditionals=”eyJ2aWV3ZXJzdGF0dXMiOiJldmVyeWJvZHkiLCJyZXN0cmljdGlvbiI6Im5vbmUiLCJ1c2Vycm9sZXMiOiIiLCJ1c2Vyc2NvcGUiOiJhbnkiLCJ1c2VyY2FwcyI6IiIsIm90aGVyc2NvcGUiOiJhbnkiLCJvdGhlcnRhZ3MiOiIiLCJkZXZpY2V0eXBlcyI6IiJ9″]PGT-A is a very early method of screening that involves checking the number of chromosomes of embryos for any abnormalities. PGT-A enables the selection of the ‘normal or Euploid’ embryo(s) for transfer giving the woman a much higher chance of achieving a pregnancy and livebirth. With age the probability of having a ‘euploid’ embryo for transfer decreases. Next Generation Sequencing (NGS) is used in PGT-A screening as it is one of the most technologically advanced means of genetic testing.
Who is it recommended for?
Older women are more likely to have eggs with abnormal chromosomes, so this screening is typically offered to women over 38 years of age. Similarly, women who have faced repeated miscarriages or implantation failure may use this test to aid the transfer of a chromosomally normal embryo giving a higher chance of a healthy livebirth.
How does it work?
For us to carry out PGT-A you will have to go through routine IVF procedures so that we can generate several viable eggs for collection. The eggs will then be fertilized in the lab and grown for 5-6 days. Only the embryos which have developed to blastocyst stage are screened and a small biopsy of cells taken. Your biopsied embryos will then be frozen in our onsite laboratory using vitrification whilst we await the results from the specialist genetics laboratory. Only embryos without any chromosomal abnormalities will be placed back in the womb via a procedure called Frozen Embryo Transfer.
Risks and side effects
This risks are similar to those outcomes of a traditional IVF cycle, including multiple births, ectopic pregnancies and miscarriage. Additionally, there may be situations whereby all the embryos biopsied may be chromosomally abnormal. It is also important to bear in mind that not all biopsied embryos will generate a result from the screening test. Typically 90% of biopsied embryos give a result. Embryos will be classified into two categories post screening: Euploid and Aneuploid.
Disclaimer to HFEA
The above procedure is considered to be a treatment add-on by the HFEA. More information can be found at https://www.hfea.gov.uk/treatments/treatment-add-ons/[/TS-VCSC-Icon-Box-Tiny][/vc_column][/vc_row][vc_row full_width=”stretch_row” el_class=”IntroBoxesRow”][vc_column width=”1/2″ css=”.vc_custom_1514733554917{margin-top: 35px !important;}”][TS-VCSC-Icon-Box-Tiny style=”boxed_left” padding_custom=”true” padding_outside=”40″ title=”PGS ( PGT-A) an Overview” title_wrap=”h2″ font_title_family=”Default:regular” title_size=”14″ title_color=”#46b4cd” title_spacing=”0″ font_content_family=”Default:regular” icon_size_slide=”16″ icon_padding=”0″ el_class=”bluecres” conditionals=”eyJ2aWV3ZXJzdGF0dXMiOiJldmVyeWJvZHkiLCJyZXN0cmljdGlvbiI6Im5vbmUiLCJ1c2Vycm9sZXMiOiIiLCJ1c2Vyc2NvcGUiOiJhbnkiLCJ1c2VyY2FwcyI6IiIsIm90aGVyc2NvcGUiOiJhbnkiLCJvdGhlcnRhZ3MiOiIiLCJkZXZpY2V0eXBlcyI6IiJ9″][/TS-VCSC-Icon-Box-Tiny][/vc_column][vc_column width=”1/2″ css=”.vc_custom_1592409338779{margin-top: 35px !important;}”][TS-VCSC-Icon-Box-Tiny style=”boxed_left” padding_custom=”true” padding_outside=”40″ title=”What Is and Isn’t Tested with PGS ( PGT-A)?” title_wrap=”h2″ font_title_family=”Default:regular” title_size=”14″ title_color=”#46b4cd” title_spacing=”0″ font_content_family=”Default:regular” icon_size_slide=”16″ icon_padding=”0″ el_class=”bluecres” conditionals=”eyJ2aWV3ZXJzdGF0dXMiOiJldmVyeWJvZHkiLCJyZXN0cmljdGlvbiI6Im5vbmUiLCJ1c2Vycm9sZXMiOiIiLCJ1c2Vyc2NvcGUiOiJhbnkiLCJ1c2VyY2FwcyI6IiIsIm90aGVyc2NvcGUiOiJhbnkiLCJvdGhlcnRhZ3MiOiIiLCJkZXZpY2V0eXBlcyI6IiJ9″][/TS-VCSC-Icon-Box-Tiny][/vc_column][/vc_row][vc_row full_width=”stretch_row” el_class=”IntroBoxesRow”][vc_column el_class=”ServiceIntroboxLeftWhite”][vc_column_text el_class=”strong-600″]
FAQ
Q: Who should consider PGT-A genetic screening?
A: PGT-A genetic screening is typically recommended for women over 38, those with repeated miscarriages, or previous implantation failures, as it increases the likelihood of transferring a chromosomally normal embryo.
Q: How does PGT-A embryo testing work?
A: During PGT-A embryo testing, embryos are cultured to the blastocyst stage (5–6 days), and a small biopsy of cells is taken. These cells are screened using Next Generation Sequencing (NGS) to identify euploid embryos, which are then frozen until a Frozen Embryo Transfer.
Q: What are the risks of PGT-A IVF?
A: Risks are similar to standard IVF, including multiple births, miscarriage, or ectopic pregnancy. Additionally, some embryos may be abnormal or fail to produce a result. Approximately 90% of biopsied embryos yield results, classified as euploid or aneuploid.
Q: How does PGT-A embryo testing work?
A: During PGT-A embryo testing, embryos are cultured to the blastocyst stage (5–6 days), and a small biopsy of cells is taken. These cells are screened using Next Generation Sequencing (NGS) to identify euploid embryos, which are then frozen until a Frozen Embryo Transfer.
[/vc_column_text][/vc_column][/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1511790456603{padding-bottom: 35px !important;}”][vc_column css=”.vc_custom_1510242553330{margin-top: 0px !important;}”][vc_row_inner][vc_column_inner][vc_custom_heading text=”Treatments” font_container=”tag:h2|text_align:center” css=”.vc_custom_1514627828652{padding-top: 35px !important;}” el_class=”titleHeader”][vc_custom_heading text=”Find out more about our related services” font_container=”tag:h3|text_align:center” el_class=”titlesubHeader” css=”.vc_custom_1511790599936{padding-bottom: 35px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner][vc_column_inner width=”1/3″][vc_column_text el_class=”ServicesMenu1″][ubermenu config_id=”servicesubmenus” menu=”66″][/vc_column_text][/vc_column_inner][vc_column_inner width=”1/3″][vc_column_text][ubermenu config_id=”servicesubmenuyell” menu=”67″][/vc_column_text][/vc_column_inner][vc_column_inner width=”1/3″][vc_column_text][ubermenu config_id=”servicesubmenus” menu=”68″][/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row full_width=”stretch_row” el_class=”Services2ColRow” css=”.vc_custom_1511790807439{background-color: #f5f8f6 !important;}”][vc_column width=”1/2″ offset=”vc_hidden-lg vc_hidden-md vc_hidden-sm vc_hidden-xs”][vc_custom_heading text=”Why Choose Us?” css=”.vc_custom_1511785280902{padding-top: 35px !important;}” el_class=”titleHeader”][vc_custom_heading text=”Here are some facts about your fertility journey with us that we’d like to share with you:” font_container=”tag:h3|text_align:left” el_class=”titlesubHeader”][vc_empty_space height=”22px”][TS-VCSC-Icon-List icon=”fa fa-check-circle” color=”#f7be68″ icon_size=”22″ font_color=”#777777″ font_size=”15″]Every evaluation and treatment plan is uniquely tailored to meet your individual needs[/TS-VCSC-Icon-List][TS-VCSC-Icon-List icon=”fa fa-check-circle” color=”#f7be68″ icon_size=”22″ font_color=”#777777″ font_size=”15″]You will have access to leading professionals, with over 35 years combined expertise, providing you with confidence and reassurance in your fertility diagnosis and subsequent treatment[/TS-VCSC-Icon-List][TS-VCSC-Icon-List icon=”fa fa-check-circle” color=”#f7be68″ icon_size=”22″ font_color=”#777777″ font_size=”15″]Our multidisciplinary team includes specialists in fertility, urology, nutrition, counselling, genetics, endocrinology, haematology and weight management to provide a comprehensive range of support as and when you need it[/TS-VCSC-Icon-List][TS-VCSC-Icon-List icon=”fa fa-check-circle” color=”#f7be68″ icon_size=”22″ font_color=”#777777″ font_size=”15″]We will work with you closely to understand your individual circumstances, identify any problems and agree with you, the best course of action to help make your dream a reality[/TS-VCSC-Icon-List][TS-VCSC-Icon-List icon=”fa fa-check-circle” color=”#f7be68″ icon_size=”22″ font_color=”#777777″ font_size=”15″]We will always be honest and open about your chances of success with treatment.[/TS-VCSC-Icon-List][TS-VCSC-Icon-List icon=”fa fa-check-circle” color=”#f7be68″ icon_size=”22″ font_color=”#777777″ font_size=”15″]Your comfort and care is always our top priority[/TS-VCSC-Icon-List][TS-VCSC-Icon-List icon=”fa fa-check-circle” color=”#f7be68″ icon_size=”22″ font_color=”#777777″ font_size=”15″]Our focus remains entirely on you as an individual, your unique needs and your wellbeing[/TS-VCSC-Icon-List][TS-VCSC-Icon-List icon=”fa fa-check-circle” color=”#f7be68″ icon_size=”22″ font_color=”#777777″ font_size=”15″]All investigations and treatments are provided within our new state-of-the-art clinic based in Elstree which offers a spacious environment with comfortable surroundings, to enhance your care and experience. We offer investigations and scans at our satellite locations too.[/TS-VCSC-Icon-List][TS-VCSC-Icon-List icon=”fa fa-check-circle” color=”#f7be68″ icon_size=”22″ font_color=”#777777″ font_size=”15″]Our friendly consultant-led team is here to support you at every step throughout your fertility journey[/TS-VCSC-Icon-List][/vc_column][vc_column width=”1/2″ offset=”vc_hidden-lg vc_hidden-md vc_hidden-sm vc_hidden-xs”][vc_empty_space][vc_single_image image=”3388″ img_size=”full”][vc_single_image image=”3391″ img_size=”full”][/vc_column][/vc_row]